Research group FOR1530

Anaerobic Biological Dehalogenation: Organisms, Biochemistry, and (Eco-)physiology

Research Unit FOR 1530

supported by the Deutsche Forschungsgemeinschaft

Sulfurospirillum multivorans, simplified scheme of organohalide respiration


NEWS (publication authors in bold are part of the research unit):

Jul 2017: The new work of Cindy Kunze, Gabriele Diekert and co-workers is published in Nature Communications! Congratulations!

Kunze C, Bommer M, Hagen WR, Uksa M, Dobbek H, Schubert T, Diekert G
Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
Nat Comm, 2017 Jul 3 (Epub ahead of print) DOI: 10.1038/ncomms15858.

June 2017: New publications are available: Stefanie Hartwig from the group of Gary Sawers (University of Halle) isolated a H2-dependent, trichlorobenzene-dechlorinating complex from the bacterium Dehalococcoides mccartyi, Tobias Goris analyzed the genome from the tetrachloroethene-respiring Sulfurospirillum halorespirans

April 2017: DehaloCon II, held in Leipzig from March 26th to March 29th, was an exciting conference with lots of new results, interesting meetings and nearly 90 attendants from four continents! Thanks to everyone for participating.

March 2017: Publication #50 is available!

Kruse S, Goris T, Wolf M, Wei X, Diekert G.
The NiFe Hydrogenases of the Tetrachloroethene-Respiring Epsilonproteobacterium Sulfurospirillum multivorans: Biochemical Studies and Transcription Analysis.
Front Microbiol. 2017 Mar 20; DOI: 10.3389/fmicb.2017.00444.

August 2016: Book on organohalide respiration/anaerobic reductive dehalogenation, edited by Lorenz Adrian from the FOR 1530 research unit and Frank Löffler out now!
Organohalide-Respiring Bacteria

August 2016: Oliver Tiedt, Matthias Boll and co-workers investigated the anaerobic degradation of 4-flouroaromatics. Their research is published in mbio: Tiedt O, Mergelsberg M, Boll K, Müller M, Adrian L, Jehmlich N, von Bergen M, Boll M.
ATP-Dependent C-F Bond Cleavage Allows the Complete Degradation of 4-Fluoroaromatics without Oxygen

January 2016: First biochemical insights into the organohalide respiratory chain of Dehalococcoides mccartyi chosen as a highlight in Environmental Microbiology! Congratulations to Anja Kublik, Lorenz Adrian and co-workers!

Kublik A, Deobald D, Hartwig S, Schiffmann CL, Andrades A, von Bergen M, Sawers RG, Adrian L.
Identification of a multiprotein reductive dehalogenase complex in Dehalococcoides mccartyi strain CBDB1 suggests a protein-dependent respiratory electron transport chain obviating quinone involvement
Environ Microbiol. 2015 Dec 31., doi:10.1111/1462-2920.13200


FOR 1530 and organohalide respiration (news and publications) now on Twitter

October 2014: SCIENCE paper out now! "Structural basis for organohalide respiration" by Martin Bommer, Cindy Kunze, Jochen Fesseler, Torsten Schubert, Gabriele Diekert and Holger Dobbek

September 2014: Unravelling organohalide respiration via genomics of Sulfurospirillum multivorans - paper in Environmental Microbiology entitled "Insights into organohalide respiration and the versatile catabolism of Sulfurospirillum multivorans gained from comparative genomics and physiological studies" by Tobias Goris, Torsten Schubert, Jennifer Gadkari, Tesfaye Wubet, Mika Tarkka, Francois Buscot, Lorenz Adrian and Gabriele Diekert

May 2014: The German Research Foundation (DFG) supports the Research Unit FOR 1530 for another three years!

June 2014: The current article on heterologous expression of reductive dehalogenases, by Anita Mac Nelly et al. was selected as a spotlight in the current issue of Applied Environmental Microbiology


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